Use of herbal products among adult patients with diabetes attending a major diabetes centre in Benghazi, Libya

Main Article Content

Rima Salama
Rehab Elfakhri

Abstract

Introduction: Diabetes mellitus is one of the most common chronic diseases worldwide and is associated with high morbidity and mortality. Herbal remedies with potential hypoglycaemic effects have been used for centuries; however, only a limited number have undergone rigorous scientific evaluation to establish their safety and efficacy.


Aim: To investigate the use of traditional herbal remedies among adult patients with diabetes attending a major diabetes centre in Benghazi, Libya.


Methods: A cross-sectional study was conducted among adult patients with diabetes attending a major diabetes centre in Benghazi, Libya. Data were collected through face-to-face interviews using a structured questionnaire covering sociodemographic characteristics, clinical characteristics, and herbal product use. Data were analysed using SPSS, and associations between herbal use and sociodemographic and clinical variables were examined.


Results: A total of 176 patients participated (response rate: 96.2%). Most participants were female, aged 46- 75 years, had no formal education, were unemployed, had low incomes, had diabetes for more than 10 years, were receiving both insulin and oral antidiabetic drugs, and had one or more comorbidities. Use of herbal products was reported by 19.9% of participants. No significant associations were observed between herbal use and sociodemographic or clinical variables (p > 0.05). Cinnamon and olive leaves were the most commonly used herbal remedies. Among herbal users, 85.7% reported satisfaction with their use, while self-motivation (31.4%) and media influence (25.7%) were the most common reasons for use. Notably, 74.3% did not disclose herbal use to their physicians.


Conclusion: Herbal product use was reported by a relatively small proportion of participants (19.9%), with no significant sociodemographic or clinical predictors. However, most herbal users did not disclose their use to their physicians, potentially increasing the risk of herb–drug interactions and other adverse outcomes. These findings highlight the need to educate patients with diabetes about the risks of using herbal products without consulting healthcare professionals.


Keywords: Diabetes mellitus, herbal medicine, herb–drug interactions, patient disclosure, cross-sectional study, Libya

Article Details

How to Cite
Salama, R., & Elfakhri, R. (2026). Use of herbal products among adult patients with diabetes attending a major diabetes centre in Benghazi, Libya. Libyan Journal of Medical and Applied Sciences, 1–11. https://doi.org/10.64943/ljmas.2026.040401
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Articles

References

Alqathama, A., Alluhiabi, G., Baghadi, H., Aljahani, L., Khan, O., Jabal, S., Makkawi, S., & Alhomoud, F. (2020). Herbal products from the perspective of type II diabetic patients and physicians: What is the relationship? BMC Complementary Medicine and Therapies, 20(1), 65. https://doi.org/10.1186/s12906-020-2854-4

Jasim, N., & Al-Asadi, S. N. (2017). Herbal product use among diabetic patients in Nassiriya, Iraq. Middle East Journal of Family Medicine, 10(30), 40-46.

Roaeid, R. B., & Kablan Alu, A. (2003). Profile of diabetes health care at Benghazi Diabetes Centre, Libyan Arab Jamahiriya. Eastern Mediterranean Health Journal,13(1), 168–176.

International Diabetes Federation. (2025). IDF diabetes atlas (11th ed.). International Diabetes Federation. https://diabetesatlas.org/

Badri, S. A. I. (2025). Correlation and regression analysis between HbA1c, fasting blood sugar (FBS), and random blood sugar (RBS) levels in diabetic and non-diabetic patients in ElMarj, Libya. Libyan Journal of Medical and Applied Sciences, 3(3), 64–71. https://doi.org/10.64943/ljmas.v3i3.116

Selçuk Tosun, A., Zincir, H., & Eliş, E. (2019). Complementary and alternative medicine use and self-efficacy level in Turkish adults with type 2 diabetes mellitus. Cukurova Medical Journal, 44(2), 309-318. https://doi.org/10.17826/cumj.441296

Baser, T., Aypak, T., Aypak, C., & Gorpelioglu, S. (2018). Use of herbal products in type 2 diabetes mellitus patients. Family Medical Care, 1. https://doi.org/10.15761/FMC.1000106

Bayoumy, I. E., & Dawod, W. (2022). Herbal use and perceptions among patients with type 2 diabetes mellitus in Kuwait. Clinical Research Notes, 3(1). https://doi.org/10.31579/2690-8816/048

Ali, B. A. M., & Mahfouz, M. S. (2014). Herbal products Use among Patients with Type 2 Diabetes in North Sudan. Annual Research & Review in Biology, 4(11), 1827–1838. https://doi.org/10.9734/ARRB/2014/8015

Chetty, L., Govender, N., & Reddy, P. (2022). Traditional medicine use among type 2 diabetes patients in KZN. Advances in Public Health, 2022, 1-12. https://doi.org/10.1155/2022/7334080

Sonar, B., Jha, B. N., & Upadhyay-Dhungel, K. (2015). Study on use of indigenous herbal products by diabetic patients visiting diabetic centre in Nepal. Janaki Medical College Journal of Medical Sciences, 3(2), 13–20.

Acar-Tek, N., & Ağagündüz, D. (2020). Olive leaf (Olea europaea L. folium): Potential effects on glycemia and lipidemia. Annals of Nutrition and Metabolism, 76(1), 10–15. https://doi.org/10.1159/000505508

Ema, G. D., Gebeyaw, E. D., Yferu, Z. A., Mulatu, S. F., Dagnaw, A. B., Aydagnuhm, G. B., & Ayicheh, E. A. (2024). Herbal product use and its impact on glycemic control among diabetes patients at governmental hospitals in Debre Berhan, Ethiopia: A cross-sectional study. Metabolism Open, 23, 100311. https://doi.org/10.1016/j.metop.2024.100311

Takteek, T. M., Abdolla, N. S. Y., Ouheda, S. A., & Gharghar, F. (2026). Therapeutic potential and safety profiles of Libyan Thymus capitatus and Rosmarinus officinalis: Quantitative elemental analysis linked to human health guidelines. Libyan Journal of Medical and Applied Sciences. https://doi.org/10.64943/ljmas.2026.040301

DeFronzo, R. A., Ferrannini, E., Henry, R. R., Herman, W. H., Holst, J. J., Hu, F. B., Kahn, C. R., Raz, I., Shulman, G. I., Simonson, D. C., Testa, M. A., & Weiss, R. (2015). Type 2 diabetes mellitus. Nature Reviews Disease Primers, 1, 15019. https://doi.org/10.1038/nrdp.2015.19

Suliman, O., Abdullah, A. Z., AlKuhayli, S., Alqahtani, R. N., Aljohani, R., & Almaimani, R. (2025). herbal product used for the treatment of diabetes mellitus in Saudi Arabia. Cureus, 17(7), e88497. https://doi.org/10.7759/cureus.88497

Li, E., Maunder, A., Liu, J., Pandey, C., Cave, A., O’Fee, A., & Ee, C. (2025). The efficacy and safety of herbal medicines for glycaemic control and insulin resistance in individuals with type 2 diabetes: an umbrella review. BMC Complementary Medicine and Therapies, 25, 341. https://doi.org/10.1186/s12906-025-05059-7

Ashur, S. T., Shah, S. A., Bosseri, S., & Shamsuddin, K. (2017). Use of traditional medicine among type 2 diabetic Libyans. Eastern Mediterranean Health Journal, 23(5), 375–382. https://doi.org/10.26719/2017.23.5.375

Alami, Z., Aynaou, H., Alami, B., Hdidou, Y., & Latrech, H. (2015). herbal product use among diabetic patients in oriental Morocco. Journal of Pharmacognosy and Phytotherapy, 7(2), 9-17. https://doi.org/10.5897/JPP2014.0338

Rahimzade, M., Farshbaf-Khalili, A., Karimi, M., Abolhasanpour, N., Kazemi, A. H., & Mirzaei, M. (2025). The prevalence of herbal product use and related factors among diabetic patients in Tabriz, Iran, 2023: A cross-sectional study. Journal of Diabetes & Metabolic Disorders, 24(1), 36. https://doi.org/10.1007/s40200-024-01531-2

Boulares, E., Bragazzi, N. L., Chen Yin, T. S., Choi, S. J., Park, J. H., & Han, D. (2026). Assessing the safety of herbal medicine use among type 2 diabetes mellitus patients: A systematic review and meta-analysis. Complementary Therapies in Medicine, 97, 103319. https://doi.org/10.1016/j.ctim.2026.103319

Doğar, E., Akbayram, H. T., & Büyükdereli Atadağ, Y. (2025). Use of herbal products by diabetic patients in coping with health problems: a cross-sectional study from Turkey. Internal and Emergency Medicine, 20, 1353–1359. https://doi.org/10.1007/s11739-025-03938-y

Prasopthum, A., Insawek, T., & Pouyfung, P. (2022). Herbal product use in Thai patients with type 2 diabetes mellitus and its association with glycemic control: A cross-sectional evaluation. Heliyon, 8(10), e10790. https://doi.org/10.1016/j.heliyon.2022.e10790